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DENNIS M WRIGHT

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Articles Posted: 137  Links Seeded: 798
Member Since: 1/2006  Last Seen: 5/17/2012

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Thalidomide effect mystery solved

Seeded on Thu Mar 11, 2010 4:27 PM EST
Read ArticleArticle Source: BBC News
health
Seeded by Dennis M Wright
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Scientists have discovered the primary mechanism by which thalidomide causes malformed limbs in developing embryos

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Dennis M Wright

Thalidomide can be effective in the treatment of certain cancers and leprosy, but its infamous side-effect, which is known as teratogenicity, mean that for women its use remains risky and controversial.

Medical researchers would therefore like to develop drugs that mimic the action of thalidomide, but do not affect limb development.

    Reply#1 - Thu Mar 11, 2010 4:28 PM EST
    sunnybunny1269

    Wouldn't it be fine if the person treated (for cancer or leperosy) was past their child bearing years or didn't ever want to have kids? Aren't there a lot of drugs that can't be used by women that can become pregnant?

      #1.1 - Thu Mar 11, 2010 4:51 PM EST
      Reply
      Hon Lee

      The effect was known in the 50s. It has taken half a century to know the mechanism of action.

        Reply#2 - Fri Mar 12, 2010 6:41 PM EST
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